Every cell in the body needs fuel to function properly and when energy systems fail, disease follows. The United States is currently facing a metabolic health crisis, with more than one-third of adults affected by obesity or diabetes. These metabolic...
Our research explores how we learn from our mistakes—a fundamental building block of intelligent behavior. As infants learning to walk, we take unsteady steps, fall, adjust, and eventually develop stable locomotion. This iterative cycle of action, error...
We are an interdisciplinary team of neurologists, neuroscientists, engineers, and rehabilitation scientists working together to improve recovery for patients after stroke. New therapies are urgently needed to cure the staggering worldwide disability that...
Dr. Cash's research focuses on understanding the mechanisms underlying both normal and pathological cortical activity and developing novel neuroprosthetic (brain computer interfaces) approaches for treating a wide variety of neurological problems. This...
The Loggia Lab's main research questions focus on the brain mechanisms of pain in humans. We are particularly interested in the evaluation of neuroimaging metrics as potential biomarkers of clinical pain, and in the identification of brain alterations...
Re-engineering memory circuits to restore cognition in brain disorders
Adaptively responding to the environment is critical to optimal navigation of our world. The hippocampus plays a critical role in this process by generating memories of our...
Our lab is interested in the crosslinks between cerebral small vessel disease (SVD) and dementia. We use a combination of advanced neuroimaging techniques in human brain tissue and animal models to unravel the histopathological underpinnings of...
The Precision Neuroscience & Neuromodulation (PNN) program at MGH, directed by Dr. Emiliano Santarnecchi, leverages the combination of multimodal neuroimaging techniques (e.g., fMRI, DTI and PET), electrophysiology, cognitive neuroscience, computational...