Only less than 2% of the human genome encodes proteins. The rest non-coding part has long been called ‘junk’ DNA. However, we found that some of the non-coding regions are highly conserved among species and many of them act as cis-regulatory elements...
Vik Khurana M.D. Ph.D. is the inaugural incumbent of the Tracy T. Batchelor Endowed Chair in Neurology at MassGeneral Brigham, Chief of the Movement Disorders Division at Brigham and Women's Hospital and Associate Professor of Neurology at Harvard Medical...
Chronic pain and headache disorders are two leading causes of disability world-wide. Improving treatments for these conditions is a major focus of my lab as well as my clinical practice as a neurologist. The experience of pain begins with specialized...
Dr. Siddiqi is a neuropsychiatrist whose research is focused on causal mapping of human brain function and dysfunction. Using techniques such as functional connectivity MRI, his lab maps brain circuits to link brain lesions and brain stimulation sites...
Our lab’s research focuses on experimental and computational approaches to understanding the neural correlates of consciousness in humans—specifically how sleep affects the brain. With our expertise in state-of-the-art quantitative methods, we develop...
The mission of the Greka laboratory is to define fundamental aspects of membrane protein biology and dissect mechanisms of cellular homeostasis. The laboratory complements this cell biology-focused program with tools from molecular biology, genomics...
The Cox lab is investigating the role of the gut microbiota in neurologic diseases, including Alzheimer's disease, Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis. The gut microbiota is composed of trillions of bacteria, fungi...
We are interested in the fundamental mechanisms of neurodegenerative disorders like Alzheimer’s disease. Over the past century-plus, research has revealed specific proteins that misfold and are deposited in neurodegeneration, and recent discoveries have...