Our laboratory's major focus is on the development of novel methods to treat brain injury, particularly the type that leads to epilepsy. We work to identify biological targets which can stop or prevent seizures if manipulated by either brain stimulation...
Sensory information from the environment drives reflexive and motivated behaviors in all organisms. The types of information that are detected, how this information is coded by neural circuits, and the responses that they trigger are thus fundamental to...
The overarching aim of our research is to advance our understanding of the neurobiology of depression and related disorders (e.g., bipolar disorders, anxiety). The ultimate goal of this work is to identify novel targets for prevention and treatment. We...
The specific aims of the Majzoub laboratory's studies are to analyze beneficial and detrimental effects, and the regulation of, the mammalian stress response, particularly within the brain. Current research focuses on the behavioral and neuroendocrine...
Our laboratory is directed toward both 1) understanding molecular controls and mechanisms over neuron sub-type development, diversity, axon guidance-circuit formation, and degeneration-disease in the cerebral cortex (e.g. corticospinal motor neurons -...
What is hunger, and how does it guide behavior?
To answer this, and other related questions, at the level of both neurobiological mechanisms and psychological constructs, we are utilizing neuron-specific recombinase driver mice in conjunction with...
Internal and external senses
We study internal sensory systems using molecular and genetic approaches. The vagus nerve is an essential body-brain communication axis that controls vital functions of the respiratory, cardiovascular, digestive, and immune...
The goal of our laboratory is to prevent the causes of brain degeneration and loss of neuronal function. In addition, we aim to repair brain function by restoration of new neurons and glia in the brain. We have three major lines of research:
(1) Lipid...