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Biochemical/Protein Chemistry

Content tagged with Biochemical/Protein Chemistry

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Elizabeth Carson Engle

Person

The human brain is a highly organized structure containing myriad axon tracts that follow precise pathways and make predictable connections, yet only a handful of human disorders clearly resulting from errors in axon growth and guidance have been...

Jie Shen

Person

As we age, our brains lose neurons, which cannot be replenished. When neuronal loss reaches above certain threshold, people develop devastating symptoms, such as dementia for Alzheimer's and movement disability for Parkinson's. There is no disease...

Charles J. Weitz

Person

Mammalian Circadian Clocks

Circadian clocks are molecular oscillators with ~24-hour periods that drive daily biological rhythms. Such clocks are found in all of the major branches of life, and they likely represent ancient timekeeping systems important...

Vikram Khurana

Person

Vik Khurana M.D. Ph.D. is the inaugural incumbent of the Tracy T. Batchelor Endowed Chair in Neurology at MassGeneral Brigham, Chief of the Movement Disorders Division at Brigham and Women's Hospital and Associate Professor of Neurology at Harvard Medical...

Michael Greenberg

Person

Our interactions with the outside world trigger changes that are critical for proper brain development and higher cognitive function. The Greenberg laboratory has a long-standing interest in the ways in which experience-driven neural activity shapes the...

Humsa Venkatesh

Person
Overview: Our lab studies the reciprocal interactions between the central nervous system and brain cancers. Our work emphasizes the electrical components of glioma pathophysiology and highlights the extent to which the brain and its neurons can control...

Annapurna Poduri

Person
My research program has a translational mission centered around the genetics of epilepsy. We recognize that epilepsy is a common condition with many causes and that people with epilepsy experience morbidity from seizures, neurodevelopmental and...

Michael Levy

Person

Dr. Michael Levy, MD, PhD, is an Associate Professor in Neurology who was recently recruited to lead the research unit in the new Division of Neuroimmunology at the Massachusetts General Hospital. His mission is to build a combined clinical and research...

Francisco Javier Quintana

Person
The Quintana laboratory studies the regulation of the immune response by endogenous and environmental factors, with the ultimate goal of dissecting the molecular mechanisms that control the immune response and identifying novel targets for therapeutic...

Silke Nuber

Person
The Nuber lab is dedicated to studying one of the top-most genetic risk factors for Parkinson’s disease (PD) -- α-synuclein -- in unique PDlike
mice.

Characterization and behavioral consequences of human α-synuclein in mouse brain.

We use mice expressing the...