Neuropharmacology & Neurochemistry

Every cell in the body needs fuel to function properly and when energy systems fail, disease follows. The United States is currently facing a metabolic health crisis, with more than one-third of adults affected by obesity or diabetes. These metabolic...

Our lab studies the molecular and cellular basis of novel organismic physiology and behavior. We emphasize curiosity-driven science and exploration, using comparative approaches featuring a range of unusual and specialized organisms that are uniquely...

I became a scientist after learning that my wife, Sonia Vallabh, inherited a lethal genetic mutation in the PRNP gene from her late mother. Her mother had died of genetic prion disease, a rapidly progressive dementia caused by misfolding of the prion...

We seek to understand the mechanisms by which heterogenous cell types orchestrate synchronous network patterns for brain computations as fundamental as memory, which may be key to understanding the origins of pathological hypersynchrony in epilepsy...

Our research seeks to understand how protein synthesis at the synapse is used to facilitate experience-dependent changes in brain function. Advances in technology have led to an increasingly complex picture of the RNA landscape of the neuron. Specific...

My lab is developing new approaches to imaging brain cells and tissues using custom molecular probes that provide color in electron microscopy. We also have another research direction where we use time-resolved cryo-vitrification to study the...

Voluntary limb movements are fundamental to human life, as evidenced by the severe functional limitations that beset those with life-long paralysis after spinal cord injury (SCI). Humans routinely coordinate a broad range of limb movements to accomplish...

The major research interest of our laboratory is the genetic control of the development and behavior of the nematode Caenorhabditis elegans, with the goal of understanding fundamental aspects of biology and revealing insights into human disease.  The...

Our translational research focuses on applying electrophysiological measures, imaging modalities, and innovative bioengineering approaches to diagnose and treat neuromuscular disorders. These techniques include electrical impedance myography...

I study the effects of cannabis use on addiction and other health outcomes, as well at the intersection between cannabis and mental health. My research combines multi-modal neuroimaging with clinical trials and behavioral and cognitive testing to...