Neuron loss is the strongest pathological correlate of cognitive decline in Alzheimer’s disease (AD) and other neurodegenerative disorders. The overarching goal of research in the Bennett Lab is to identify the mechanisms that drive neuronal degeneration...
The Elya lab focuses on unraveling the mechanisms by which parasitic fungi manipulate animal behavior, using the lab-tractable "zombie fly" model system (Drosophila melanogaster infected with the fungal parasite Entomophthora muscae). Zombie flies flies...
Every cell in the body needs fuel to function properly and when energy systems fail, disease follows. The United States is currently facing a metabolic health crisis, with more than one-third of adults affected by obesity or diabetes. These metabolic...
The Fanning lab is focused on the role of the metablome in neurodegenerative diseases including Parkinson's disease (PD), Lewy body Dementia (LBD), and other synucleinopathies. Our research is motivated by the huge unmet medical need for mechanism-based...
Our lab studies how sensory cues become linked to adaptive or maladaptive responses through learning. Adaptive responses are necessary to develop, survive and thrive; maladaptive responses contribute to disorders across the lifespan. We study this...
My research focuses on improving neuromodulation therapies for epilepsy through patient-specific computational modeling, advanced neuroimaging, and brain network analysis. Many epilepsy patients do not respond to medication, and while surgery is an option...
We are broadly interested in molecular programs that shape cognition and behavior. Our current work centers on circulating factors (i.e. hormones)— produced by peripheral organs, influenced by environment and somatic state, and readily measured in human...
The human brain is a mosaic structure with significant genetic diversity arising from post-zygotic (i.e., somatic) genetic variation. The overarching mission of our lab is to examine how this somatic variation contributes to both typical and pathological...
The Cox lab is investigating the role of the gut microbiota in neurologic diseases, including Alzheimer's disease, Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis. The gut microbiota is composed of trillions of bacteria, fungi...
Human-machine integration seeks to harmonize advanced engineering with the human body’s complex biological systems, a task that remains challenging due to the limitations of current technology and the separation between disciplines like engineering...