Rachelle Gaudet
Professor of Molecular and Cellular Biology
My lab is broadly interested in the mechanisms of signaling and transport across cellular membranes. Our research encompasses several protein families: Nramp transporters that use a proton gradient to facilitate the entry of divalent ions (iron and manganese in particular) into cells; non-classical cadherins involved in cellular adhesion and signaling; ABC transporters that use ATP to fuel substrate transport; and TRP channels important to sensing temperature and painful stimuli. We use a variety of cell-based and in vitro biochemical assays, x-ray crystallography, and computational techniques (molecular dynamics simulations and bioinformatics analyses) to discover how these important proteins function in cells.
Contact Information
Harvard University
Dept. of Molecular & Cell Biology
52 Oxford St., NW Bldg. 311.13
Cambridge, MA 02138
Dept. of Molecular & Cell Biology
52 Oxford St., NW Bldg. 311.13
Cambridge, MA 02138
p: 617-495-5616