Every cell in the body needs fuel to function properly and when energy systems fail, disease follows. The United States is currently facing a metabolic health crisis, with more than one-third of adults affected by obesity or diabetes. These metabolic...
Our lab studies the molecular and cellular basis of novel organismic physiology and behavior. We emphasize curiosity-driven science and exploration, using comparative approaches featuring a range of unusual and specialized organisms that are uniquely...
The brain-CSF interface: Neural stem cells and disease
Defined numbers of neural precursor cells are remarkably synchronized in their task to form the brain, yet no central command coordinating this process has been identified. Neural precursors divide...
The brain allows animals to successfully interact with a natural world that is rich with opportunity and rife with danger. These interactions are mediated by sensation and movement, which are used by animals to learn about their environment and to make...
We seek to understand the mechanisms by which heterogenous cell types orchestrate synchronous network patterns for brain computations as fundamental as memory, which may be key to understanding the origins of pathological hypersynchrony in epilepsy...
Our research seeks to understand how protein synthesis at the synapse is used to facilitate experience-dependent changes in brain function. Advances in technology have led to an increasingly complex picture of the RNA landscape of the neuron. Specific...