The Fanning lab is focused on the role of the metablome in neurodegenerative diseases including Parkinson's disease (PD), Lewy body Dementia (LBD), and other synucleinopathies. Our research is motivated by the huge unmet medical need for mechanism-based...
My research focuses on improving neuromodulation therapies for epilepsy through patient-specific computational modeling, advanced neuroimaging, and brain network analysis. Many epilepsy patients do not respond to medication, and while surgery is an option...
The human brain is a mosaic structure with significant genetic diversity arising from post-zygotic (i.e., somatic) genetic variation. The overarching mission of our lab is to examine how this somatic variation contributes to both typical and pathological...
The Cox lab is investigating the role of the gut microbiota in neurologic diseases, including Alzheimer's disease, Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis. The gut microbiota is composed of trillions of bacteria, fungi...
Dr. Siddiqi is a neuropsychiatrist whose research is focused on causal mapping of human brain function and dysfunction. Using techniques such as functional connectivity MRI, his lab maps brain circuits to link brain lesions and brain stimulation sites...
We are interested in the fundamental mechanisms of neurodegenerative disorders like Alzheimer’s disease. Over the past century-plus, research has revealed specific proteins that misfold and are deposited in neurodegeneration, and recent discoveries have...
Only less than 2% of the human genome encodes proteins. The rest non-coding part has long been called ‘junk’ DNA. However, we found that some of the non-coding regions are highly conserved among species and many of them act as cis-regulatory elements...
Our lab’s research focuses on experimental and computational approaches to understanding the neural correlates of consciousness in humans—specifically how sleep affects the brain. With our expertise in state-of-the-art quantitative methods, we develop...
As we age, our brains lose neurons, which cannot be replenished. When neuronal loss reaches above certain threshold, people develop devastating symptoms, such as dementia for Alzheimer's and movement disability for Parkinson's. There is no disease...