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Broad Institute

Content tagged with Broad Institute

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Eric Minikel

Person
I became a scientist after learning that my wife, Sonia Vallabh, inherited a lethal genetic mutation in the PRNP gene from her late mother. Her mother had died of genetic prion disease, a rapidly progressive dementia caused by misfolding of the prion...

Evan Macosko

Person

The human brain—and the diseases that afflict it—present unique challenges for experimental study, chief among them being tissue availability (only at postmortem) and profound cell non-autonomy in tissue function. Our lab seeks to develop technologies...